Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Size comparison of the acceptor-binding pocket of UGT71G1 with PaGT3. The highlighted helix of UGT71G1 (tan, PDB#: 2ACW) shows similarity in orientation with the highlighted portion of PaGT3 from P. americana (pink, PDB: 7VEL), relative to the capsaicin substrate of PaGT3 (dark pink). However, the helix in PaGT3 is positioned further away from the acceptor pocket, which corresponds to an increased pocket size in PaGT3 compared to UGT71G1, which allows binding to capsaicin.
