Table 3.
Odds ratios relating the thrombus characteristics to the outcome measures in the univariate analysis. Numbers in the parenthesis show a 95% CI. Functional outcome: the reversed mRS (OR < 1 indicates a worse outcome); FPS: first-pass success, eTICI 2b-3 with a single thrombectomy device pass; eTICI2b+: successful reperfusion, eTICI ≥ 2b at the end of the procedure; HUs: Hounsfield Units; TAI: Thrombus Attenuation Increase; SD: Standard Deviation; OR: odds ratio; CI: confidence interval; NCCT: Non-contrast Computed Tomography; CTA: Computed Tomography Angiography; MCC: Maximum Cross Correlation and “†” and the bold text indicate a statistically significant relationship.
| VOLUME | DENSITY | PERVIOUSNESS | HETEROGENEITY | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
Volume (per 0.1 mL) |
NCCT median (per 10 HU) |
TAIQ1
(per 10 HU) |
TAIQ2 (per 10 HU) |
TAIQ3 (per 10 HU) |
TAIMCC (per 10 HU) |
CTA median (per 10 HU) |
CTA SD (per 10 HU) |
NCCT SD (per 10 HU) |
||
| Functional Outcome |
Registry |
0.91 † (0.87–0.95) |
0.98 (0.87–1.09) |
1.14 † (1.07–1.21) |
1.10 † (1.04–1.15) |
1.05 † (1.02–1.09) |
1.11 † (1.05–1.17) |
1.09 † (1.03–1.15) |
0.93 † (0.87–0.99) |
0.87 † (0.77–0.98) |
| NO IV | 0.91 (0.81–1.02) |
1.15 (0.81–1.62) |
1.20 † (1.01–1.44) |
1.22 † (1.04–1.42) |
1.16 † (1.02–1.30) |
1.17 † (0.01–1.35) |
1.23 † (1.06–1.44) |
1.14 (0.94–1.40) |
0.76 (0.53–1.09) |
|
| FPS | Registry | 0.94 (0.88–1.00) |
0.93 (0.80–1.08) |
1.07 (0.97–1.18) |
1.04 (0.96–1.12) |
1.03 (0.98–1.08) |
1.05 (0.97–1.14) |
1.02 (0.96–1.10) |
1.01 (0.92–1.12) |
0.97 (0.84–1.13) |
| NO IV | 0.92 (0.79–1.06) |
0.70 (0.44–1.12) |
1.01 (0.82–1.25) |
1.07 (0.89–1.29) |
1.11 (0.95–1.29) |
1.05 (0.87–1.27) |
1.00 (0.84–1.20) |
1.06 (0.84–1.34) |
0.55 † (0.31–0.98) |
|
| eTICI2b+ | Registry | 1.01 (0.95–1.06) |
0.93 (0.82–1.05) |
0.96 (0.89–1.03) |
0.97 (0.91–1.03) |
0.98 (0.94–1.03) |
0.98 (0.92–1.05) |
0.95 (0.90–1.01) |
0.96 (0.89–1.04) |
0.88 † (0.78–0.99) |
| NO IV | 0.99 (0.84–1.17) |
1.20 (0.72–2.00) |
0.94 (0.70–1.26) |
0.94 (0.75–1.17) |
0.98 (0.83–1.16) |
1.00 (0.81–1.23) |
0.97 (0.77–1.22) |
1.03 (0.76–1.38) |
0.75 (0.47–1.21) |
|