Table 1.
Demographic data and neuropathological assessments of the cohort.
| Case | Age at Death | Sex | Disease Duration, Year | PMI, Hour | Clinical Phenotypes |
Pathological Diagnosis | Braak LBD Stage | NIA-AA ADNC | DV200, % |
|---|---|---|---|---|---|---|---|---|---|
| HS1 | 73 | M | 8 | 9 | DLB | LBD | 5 | Intermediate, A2B3C2 | 90 |
| HS2 | 79 | M | 6 | 8.5 | DLB | LBD | 6 | Intermediate, A3B2C2 | 86 |
| HS3 | 80 | M | 7 | 5 | DLB | LBD | 4 | High, A3B3C2 | 88 |
| HS4 | 92 | F | 10 | NA | DLB | LBD | 5 | Intermediate, A3B2C1 | 86 |
| LS1 | 59 | F | 1 * | 12.5 | DLB | LBD | 5 | High, A3B3C3 | 73 |
| LS2 | 65 | F | 12 | 3 | DLB | LBD | 4 | High, A3B3C3 | 85 |
| LS3 | 72 | M | 7 | 6.5 | DLB | LBD | 5 | High, A3B3C3 | 88 |
Note: *, The cause of death: a car accident. Abbreviations: DLB, dementia with Lewy body; HS, α-syn high seeder; LS, α-syn low seeder; NA, not available; NIA-AA ADNC, National Institute of Aging-Alzheimer’s Association Alzheimer’s disease neuropathological change; PMI, post-mortem interval.