Figure 4.

Clustered heatmap of the differentially expressed proteins in mouse skeletal muscle tissue. Clustered heatmap of the 119 differentially expressed proteins in mouse muscle tissue, filtered with log₂FC threshold set to exclude the interval −0.3, 0.3, allowing p < 0.05. Yellow color represents upregulation, while blue represents downregulation in HFD + NMN-treated group compared to HFD group. From left to right, expression values (log₂ transformed) for replicates (5 biological × 3 technical) are shown for the HFD group and for the HFD + NMN-treated group, followed by significance values of the comparison to HFD group.