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. 2024 Feb 24;25(5):2642. doi: 10.3390/ijms25052642

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Pulmonary absorption of exosomes with intravenous, PA balloon catheter-guided, and nebulized delivery. (A) Xenogen imaging of uptake of DiR-labeled PEP in the lungs for intravenous, PA balloon catheter-guided, and nebulized delivery. (B) Western blot demonstrating presence of PEP in control lung (ctrl) tissue compared to lung tissue from intravenous, PA balloon catheter-guided, and nebulized deliveryusing exosomal protein CD63 (green) and loading control actin (red). (C) Quantification (n = 3) of mean fluorescent signal (±SEM) of CD63 normalized to actin loading control; dotted line represents level of control (ctrl).