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Histologic evaluation of pulmonary exosome delivery with intravenous, PA balloon catheter-guided, and nebulized delivery. (A) Immunohistochemical staining of lung tissue with CD63 (brown) with hematoxylin counterstain (blue) with scale bar 100 µm. (B) Mean (±SEM) ratio of CD63 area to total lung tissue area in untreated (control), intravenous, PA balloon catheter-guided, or nebulization delivery methods (n = 9). * p < 0.05, *** p < 0.001, and **** p < 0.0001 using Kruskal–Wallis test.
