Figure 2.

Limitation of productivity by the “cell density effect.” (a) Cell‐specific and (b) volumetric productivity of ChAdOx1 nCov‐19 over a range of viable cell densities at infection. An MOI of 5 was used, and flasks were harvested at 44 h. Data are given as median and range (if large enough to display) from duplicate shake flasks. Productivity values were based on viral particles measured by qPCR. Viable cell density was measured at infection. MOI, multiplicity of infection; qPCR, quantitative polymerase chain reaction; VPs, viral particles.