Figure 2.
Lowering release probability reveals SYT7-mediated facilitation at striatal terminals. A, Representative dLight transients in WT and Syt7 KOs recorded from the same brain slice in high and low Cae. B, Response amplitudes recorded from slices where Cae was lowered from 2 to 0.5 mM (WT, N = 14; Syt7 KO, N = 13). C, Representative fluorescent transients evoked by paired-pulse stimulation at 50 ms intervals (dark traces) and single stimuli (light traces) in 0.5 mM Cae. D, Average paired-pulse ratios in 0.5 mM Cae at varying interstimulus intervals in WT (N = 15) and Syt7 KOs (N = 15). E, Ratio of average WT and Syt7 KO PPR, showing a single exponential fit with 196 ms decay.