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. 2023 Dec 7;44(1):17–28. doi: 10.1002/npr2.12399

TABLE 2.

Ki values of the candidate drugs.

DRD4 DRD2 D4/D2 α1
Pipamperone 5.1 120.0 0.04 66.0 Li et al. 96
Clozapine 40.0 152.0 0.26 123.0 Schotte et al. 97
63.0 72.0 0.86 109.0 Ishiyama et al. 98
47.0 125.0 0.38 Bymaster et al. 100
13.0 74.0 0.17 Patel et al. 102
Asenapine 1.1 1.3 0.85 1.2 Stoner et al. 99
Olanzapine 21.0 72.0 0.29 109.0 Ishiyama et al. 98
26.0 11.0 2.36 Bymaster et al. 100
57.3 10.5 5.46 Rasmussen et al. 101
Perospirone 1.8 1.3 1.38 2.5 Schotte et al. 97
Mosapramine 3.2 1.8 1.66 43.0 Schotte et al. 97
Risperidone 16.0 3.3 4.84 2.3 Schotte et al. 97
7.5 4.9 1.53 5.0 Ishiyama et al. 98
Haloperidol 15.0 2.0 7.50 Li et al. 96
11.0 1.4 7.80 19.0 Schotte et al. 97
5.0 2.0 2.50 12.0 Ishiyama et al. 98
1.6 1.0 1.60 Bymaster et al. 100
2.3 1.4 1.64 Patel et al. 102
Spiperone 1.4 0.053 26.40 25.0 Li et al. 96