. 2024 Feb 28;15:1297841. doi: 10.3389/fendo.2024.1297841

Table 3.

Behavioral intervention compared with control for PCOS patients.

Outcome		Study included number	Heterogeneity		Effect model	Meta analysis
Outcome		Study included number	P value	I²	Effect model	Relative effect (95%CI)	P value
Anthropometric measurements	Weight loss	4	1.00	0%	Fixed	-1.07 (-2.10, -0.03)	0.04
	Body mass index	6	0.002	73%	Random	-1.12 (-1.92, -0.33)	0.006
	Waist circumference	4	0.88	0%	Fixed	-3.97 (-5.64, -2.29)	<0.00001
Clinical outcomes	Depression	3	<0.00001	92%	Random	-1.21 (-2.35, -0.07)^a	0.04
	Menstrual problems	3	0.93	0%	Fixed	0.17 (-0.11, 0.46)	0.23
	Hirsutism	3	0.16	46%	Fixed	-0.26 (-0.53, 0.00)	0.05
	Emotion	3	0.79	0%	Fixed	0.11 (-0.13, 0.36)	0.35
	Infertility	3	0.28	22%	Fixed	0.24 (-0.06, 0.54)	0.11
	Weight	2	0.40	0%	Fixed	0.58 (0.15, 1.02)	0.008
Biochemical indexes	High-density lipoprotein	2	0.08	67%	Random	0.03 (-0.12, 0.18)	0.69
	Low-density lipoprotein	2	0.76	0%	Fixed	-0.04 (-0.20, 0.12)	0.65
	Systolic blood pressure	2	0.49	0%	Fixed	1.31 (-2.36, 4.98)	0.48
	Diastolic blood pressure	2	0.42	0%	Fixed	-0.32 (-3.04, 2.40)	0.82
	HOMA-IR	3	0.61	0%	Fixed	-0.14 (-0.47, 0.19)	0.41
	Triglycerides	3	0.25	27%	Fixed	-0.16 (-0.27, -0.05)	0.004
	Total cholesterol	2	0.55	0%	Fixed	-0.04 (-0.23, 0.16)	0.71
	Testosterone	3	0.02	76%	Random	0.30 (-0.18, 0.78)^a	0.22
	Fasting glucose	3	0.06	64%	Random	0.00 (-0.21, 0.21)	0.99
	Fasting insulin	3	0.41	0%	Fixed	-0.56 (-2.79, 1.68)	0.63
	HbA1C	2	0.95	0%	Fixed	-0.34 (-0.68, -0.00)^a	0.05
	SHBG	2	0.63	0%	Fixed	0.05 (-0.27, 0.26)^a	0.78

HOMA-IR, homeostasis model assessment as an index of insulin resistance; HbA1C, hemoglobin A1C; SHBG, sex hormone binding globulin; ^a, standardized mean difference.