Table 2.

Acute withdrawal adverse events associated with naloxone use treatment of opioid use disorder (14, 42).

• Body aches • Fever (pyrexia), chills • Sweating (hyperhidrosis) • Runny nose • Sneezing • Piloerection • Yawning • Weakness (asthenia) • Shivering or tremor • Nervousness, restlessness, or irritability • Diarrhea, nausea, vomiting • Abdominal cramps • Increased blood pressure, tachycardia • Aggressive behavior