Table 2.

Invitro and In vivo evidences of therapeutics benefits offered by kefir “a functional dairy foods.”

Condition	Activity	Subject	Effect	References
In vivo	Anticancer activity	Mice	The consumption of milk kefir and soymilk kefir has been shown to considerably suppress the formation of tumors in mice and dramatically boost IgA levels.	(86)
Vitro	Antioxidant activity	–	Kefir has a strong affinity for binding the superoxide radical and the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, in addition to its ability to suppress linoleic acid peroxidation.	(93)
In vivo	Gut health improvement	Mice(two groups of 6)	Bifidogenic growth is one of the probiotic effects of kefir on the gut’s bacterial population.	(77)
Vivo	Antimicrobial properties	Mouse	Antagonistic activity was shown to protect against potentially dangerous microbes (Salmonella typhimurium).	(80)
In vitro	Antimicrobial properties	–	Researchers have discovered that Lentilactobacillus kefiri B6 is immune to the harmful effects of bile and exhibits antipathogenic capabilities.	(95)
Vivo	Inflammatory bowel disease (IBD)	Rat	Reduces the amount of diarrhea and damage to the mucosal wall caused by the illness at the macroscopic level.	(96)