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. 2023 Oct 18;397(4):2485–2496. doi: 10.1007/s00210-023-02768-z

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© The Author(s) 2023

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Fig. 4 — Relative mRNA expression of total NR1I2 (A) or its splice variants (B) in primary human hepatocytes after treatment with rifampicin or rifabutin (both 10 μM) for 48 h. Data points shown are the mean ± S.D. of hepatocyte samples (pooled from three independent experiments), evaluated by two technical replicates (PCR runs). Statistical significance was evaluated by non-parametric Kruskal-Wallis test and Dunn’s test (correcting for multiple comparisons), comparing all solvent control hepatocyte samples with all rifampicin-treated or rifabutin-treated hepatocyte samples