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. 2024 Mar 12;14:5987. doi: 10.1038/s41598-024-56530-3

Table 2.

Single nucleotide polymorphisms with significant effects on mandibular condyles traits.

Mandibular condyles trait Gene SNP (1/2)* Genotypes Model coefficients B-H P value Model fit measures Power estimate
β 95% CI P value F test P value Adjusted R2
lower upper
Symmetric PC2 BMP2 rs1005464 (A/G) AG vs. GG − 0.011 − 0.021 − 0.002 0.020 0.140 0.007 0.090 0.913
AG + AA vs. GG − 0.011 − 0.020 − 0.002 0.014 0.098 0.003 0.098 0.933
Asymmetric PC4 SMAD6 rs2119261 (T/C) CT vs. CC − 0.003 − 0.006 0.000 0.030 0.210 0.009 0.084 0.525
Symmetric log centroid size BMP2 rs1005464 (A/G) AG vs. GG 0.043 0.013 0.073 0.005 0.035  < 0.001 0.165 0.995
AG + AA vs. GG 0.043 0.014 0.071 0.004 0.028  < 0.001 0.173 0.997
Mahalanobis shape FA scores BMP2 rs1005464 (A/G) AA vs. GG 0.917 0.195 1.639 0.013 0.091 0.011 0.082 0.890
AA vs. AG + GG 0.828 0.117 1.539 0.023 0.109 0.009 0.076 0.865
BMP4 rs17563 (G/A) GG vs. AA 0.641 0.053 1.228 0.033 0.116 0.024 0.065 0.803
GG vs. AG + AA 0.563 0.052 1.075 0.031 0.109 0.012 0.071 0.845
Condylar volume BMP2 rs1005464 (A/G) AG vs. GG 235.6 43.0 428.2 0.018 0.126  < 0.001 0.191 0.996
AG + AA vs. GG 232.9 50.8 415.0 0.014 0.098  < 0.001 0.192 0.997

SNP—single nucleotide polymorphism, CI—confidence interval, B-H—Benjamini–Hochberg procedure, PC—principal component, log—natural logarithm, FA—fluctuating asymmetry.

* (1 = minor allele / 2 = major allele).

Common homozygous genotypes were established as the reference category in the models.