Table 2.

Relationship between UBQLN2 genotype, granule complexity and fluorescence recovery.

Group	n	Mean	Median	SD	Versus within genotype low complexity	Versus WT of same complexity
WT_low	8	0.779	0.777	0.168	N/A	N/A
WT_high	9	0.707	0.677	0.224	Non-significant	N/A
A282V_low	8	0.805	0.862	0.188	N/A	Non-significant
A282V_high	7	0.67	0.744	0.224	Non-significant	Non-significant
M446R_low	10	0.873	0.886	0.088	N/A	Non-significant
M446R_high	7	0.83	0.842	0.115	Non-significant	Non-significant
P497H_low	5	0.863	0.835	0.1	N/A	Non-significant
P497H_high	7	0.593	0.65	0.198	Non-significant	Non-significant
P497S_low	5	0.81	0.791	0.149	N/A	Non-significant
P497S_high	12	0.706	0.673	0.154	Non-significant	Non-significant
P506T_low	6	0.723	0.751	0.136	N/A	Non-significant
P506T_high	8	0.401	0.381	0.159	Significant	Significant

Granules with a mean complexity score of 1–2 were grouped into “low complexity”, and those with a score of 3–4 as “high complexity”. mean = mean mobile fraction, n = the number of granules observed in each complexity category per genotype. For each genotype, mean mobile fraction was compared between low complexity and high complexity granules. Mean mobile fraction was also compared to WT granules of like-complexity. Significance is reported for those comparisons that reached a p value < 0.05 using Sidak’s multiple comparions test.

Significant values are in bold.