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. 2024 Jan 23;25(3):1541–1569. doi: 10.1038/s44319-023-00051-z

Table 1.

Analysis of SOX substrate-targeting motif.

Subset: Log2FC (3 dpi/Uninduced # circRNA # circRNA in circAtlas # UGAAG motifs # Motifs per circRNA # Motifs per 1000 nt UGAAG+ circRNA
# circRNA % Total
Upregulated: ≥0.5 42 39 circRNA (22,459 nt) 71 1.9 3.2 37 88%
Unchanged: <0.5 and >−0.5 28 28 circRNA (20,975 nt) 95 3.7 4.5 26 93%
Downregulated: ≤−0.5 30 25 circRNA (12,900 nt) 104 4.7 8.1 22 73%

The presence of SOX substrate-targeting motifs “UGAAG” was determined for subsets of human circRNAs from our KSHV reactivation model (iSLK-BAC16).