Table 2.
Descriptive analysis and comparison of hand OA patients according to EHOA.
| Erosive (n = 303) |
Non-erosive (n = 736) |
|||
|---|---|---|---|---|
| Mean (SD) | Mean (SD) | OR (95%CI) | p | |
| Age at diagnosis | 59 (8.17) | 65 (8.97) | 0.93 (0.92–0.95) | < 0.001 |
| BMI | 30 (12.96) | 29 (24.61) | 1.00 (0.98–1.01) | 0.653 |
| Abdominal perimeter (cm) | 93 (12.71) | 96 (11.98) | 0.98 (0.97–0.99) | 0.002 |
| Total AUSCAN | 54 (26.92) | 41 (29.50) | 1.02 (1.01–1.02) | < 0.001 |
| Pain AUSCAN | 56 (27.81) | 43 (31.85) | 1.01 (1.01–1.02) | < 0.001 |
| Stiffness AUSCAN | 54 (32.88) | 39 (36.00) | 1.01 (1.01–1.02) | < 0.001 |
| Function AUSCAN | 54 (28.44) | 40 (30.28) | 1.02 (1.01–1.02) | < 0.001 |
| ESR | 20 (13.41) | 19 (14.91) | 1 (0.99–1.01) | 0.408 |
| CRP (mg/dL) | 0 (0.54) | 0 (1.01) | 0.95 (0.75–1.12) | 0.597 |
| n (%) | n (%) | |||
| Sex | ||||
| Male | 38 (12.54) | 143 (19.43) | 0.6 (0.40–0.87) | 0.009 |
| Female | 265 (87.46) | 593 (80.57) | 1.00 | |
| Hypertension | 114 (37.75) | 385 (52.52) | 0.55 (0.41–0.72) | < 0.001 |
| Diabetes | 57 (18.87) | 129 (17.67) | 1.09 (0.76–1.53) | 0.641 |
| Dyslipidemia | 168 (55.45) | 431 (58.72) | 0.88 (0.67–1.15) | 0.344 |
| Hypertriglyceridemia | 47 (15.72) | 121 (17.26) | 1.09 (0,76–1.53) | 0.550 |
| Low HDL | 30 (9.97) | 65 (9.25) | 0.88 (0.67–1.15) | 0.344 |
| MetS | 50 (16.50) | 152 (20.82) | 0.75 (0.53–1.07) | 0.114 |
| Osteoporosis | 44 (14.52) | 122 (16.58) | 1.33 (0.93–1.88) | 0.116 |
| Osteopenia | 30 (9.90) | 77 (10.46) | 0.86 (0.58–1.24) | 0.417 |
| Smoking habit | ||||
| Never | 177 (58.42) | 482 (65.94) | 1.00 | |
| Current | 39 (12.87) | 83 (11.35) | 1.28 (0.84–1.94) | 0.243 |
| Former | 87 (28.71) | 166 (22.71) | 1.43 (1.05–1.95) | 0.024 |
| Psoriasis | 21 (6.93) | 66 (9.02) | 0.9 (0.62–1.29) | 0.557 |
| Knee OA (KL > I) | 155 (53.26) | 558 (77.50) | 0.33 (0.25–0.44) | < 0.001 |
| Hip OA | 109 (37.33) | 406 (57.43) | 0.44 (0.33–0.58) | < 0.001 |
| Inflammatory hand OA | 80 (26.49) | 37 (5.08) | 6.74 (4.44–10.24) | < 0.001 |
| Nodular hand OA | 290 (96.03) | 566 (78.72) | 6.53 (3.57–11.95) | < 0.001 |
| Thumb base OA | 160 (53.16) | 489 (67.45) | 0.55 (0.42–0.72) | < 0.001 |
| Positive RF | 24 (8.42) | 57 (8.77) | 0.96 (0.58–1.57) | 0.856 |
| Positive ACPA | 3 (1.11) | 9 (1.52) | 0.72 (0.19–2070) | 0.630 |
BMI, body mass index (Kg/m2); HDL, high-density lipoprotein; MetS, metabolic syndrome; Knee OA, OA at least in one knee; Hip OA, OA at least in one hip; EHOA, erosive hand osteoarthritis at least in one hand; Inflammatory hand OA, OA at least in one hand; Nodular hand OA, OA at least in one hand; Thumb base OA, OA at least in one hand; ESR, erythrocyte sedimentation rate (mmHg); CRP, C-reactive protein (mg/dL); RF, rheumatoid factor; ACPA, anti-citrullinated protein antibodies.
Significant values are in [bold].