Table 4.
Performance evaluation metrics of eight classifiers for reduced dataset generated by proposed approach consisting of PL+ and PL- molecules based on 10-fold cross validation.
| Classifiers | Sensitivity | Specificity | Accuracy | AUC | MCC |
|---|---|---|---|---|---|
| Navie Bayes | 85.3 | 70.6 | 77.9 | 0.846 | 0.565 |
| SMO | 81.4 | 68.6 | 75.0 | 0.750 | 0.504 |
| IBK | 87.3 | 87.3 | 87.3 | 0.811 | 0.745 |
| RARF | 88.2 | 84.3 | 86.3 | 0.925 | 0.726 |
| PART | 71.6 | 72.5 | 72.1 | 0.778 | 0.441 |
| JRip | 74.5 | 80.4 | 77.5 | 0.811 | 0.550 |
| RandomForest | 84.3 | 84.3 | 84.3 | 0.915 | 0.686 |
| J48 | 74.5 | 75.5 | 75.0 | 0.752 | 0.500 |