Figure 1.

Sequencing of plasma sncRNAs from healthy individuals and Mtb-infected patients

(A) Schematic representation of the sncRNA sequencing for T4 PNK-treated plasma RNAs. (B) Abundance of plasma sncRNAs annotated to the indicated RNAs. The read counts of these sncRNAs were normalized using the read counts of the spike-in RNAs. (C) Proportions of plasma sncRNAs annotated to the indicated RNAs. Average values from the four samples are shown. (D) Schematic showing examples of the different classes of tRNA-derived sncRNAs. (E) Abundances of tRNA-derived sncRNAs subclassified into the indicated categories. Read counts, normalized using the spike-in RNAs, are shown. (F) Proportion of tRNA-derived sncRNAs, represented as average values across the four samples.