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Bi-directional MR sensitivity analysis of the potentially causal effect of correctly identifying matches (UKB-ID 20023) on subcortical white matter volume (UKB-ID 26553) (A-B) and vice versa (C-D). (A) and (C) Scatter plots showing associations of individual SNPs with exposure and outcome variables. Coloured lines indicate effect estimates from regression fits using different MR methods. (B) and (D) Funnel plots of single-SNP effect estimates and corresponding inverse standard errors.
