Cell-viability
assessment of eqACPCs cultured directly on MEW scaffolds
in expansion medium. (A) Live (green)/dead (red) viability assay maximum
projection fluorescent microscopy images on D1 and D7. N.B. Background
staining of MEW fibers is observable in these images, likely due to
the physisorption of the less hydrophobic surfaces. n = 2; scale bar = 200 μm. (B) Metabolic activity assessment
of constructs on D1, D4, and D7. n = 4, data shown
as the mean ± standard deviation. Significance values: n.s. p > 0.05, *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001. (i) Metabolic activity quantification
normalized against DNA content of sample. Separate assay results are
displayed as ii. Metabolic assay, and as iii. DNA quantification.