Table 1.

Biochemical and metabolic parameters of STD vs. HFD group.

Parameters	STD	HFD	p
Body weight (g)	32.78 ± 0.662	41.78 ± 1.164	<0.0001
Food intake (g/mouse/24 h)	3.69 ± 0.193	2.90 ± 0.050	<0.0001
Total cholesterol (mg/dL)	100.1 ± 4.478	148.4 ± 6.679	<0.0001
LDL cholesterol (mg/dL)	10.65 ± 1.369	16.75 ± 2.238	0.0356
HDL cholesterol (mg/dL)	78.11 ± 3.728	114.2 ± 4.983	<0.0001
Triglycerides (mg/dL)	64.13 ± 3.404	94.78 ± 10.80	0.0008
Glycemia (mg/dL)	148.2 ± 9.843	197.4 ± 15.98	0.0229
BUN (mg/dL)	26.33 ± 1.373	21.09 ± 0.7058	0.0037
AST/GOT (IU/L)	8.54 ± 1.268	17.65 ± 1.877	0.0014
ALT/GPT (IU/L)	1.60 ± 0.549	5.50 ± 1.654	0.0508
C-peptide (pM)	33.72 ± 3.845	75.04 ± 28.10	0.0288
HOMA-IR index	12.92 ± 1.931	39.48 ± 17.94	0.0206

BUN, blood urea nitrogen; AST/GOT, aspartate aminotransaminase; ALT/GPT, alanine aminotransaminase.