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. 2023 Nov 4;14(3):1345–1361. doi: 10.1016/j.apsb.2023.11.005

Figure 7.

Figure 7

Abscopal effect of “Gemini nanoimmunoregulators” and metastasis inhibition. (A) Photographs and (B) growth curves of distal tumors. (C) Microscopic images of distal tumor sections with IF staining of Ki67, CD4, CD8, and Foxp3 (scale bar = 100 μm), and (D) further quantified by Image J. (E) Therapeutic schedule of 4T1 lung metastatic model. (F) Representative photographs of lung tissues with tumor metastasis and HE staining images (scale bar = 2 mm). (G) Microscopic images of lung sections with immunohistochemistry analysis of Ki67 (scale bar = 100 μm) and IF staining of CD4 and CD8 (scale bar = 50 μm).