FIG. 4.
Pathology and transgene expression in livers, lungs, and intestines of CD4C/HIVWT Tg mice. (A and B) Non-Tg and Tg (F17018) lungs, respectively. Note the extensive interstitial pneumonitis in the Tg lung. (C to E) Tg expression is seen in interstitial infiltrating cells and alveolar macrophages in the lung (F17001) (C) (S, alveolar space), in Kupffer cells (liver macrophages) (F17001) (D), and in cells in the lamina propria of the small intestine (F17018) (E). Magnifications, ×190 (A to D) and ×400 (insets to panels C and D panel E). The counterstain was hematoxylin and eosin.