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Impact of Immune-Deficient Mouse Host Strain on Human Chimerism. Three strains of immune-deficient mice were humanized with neonatal thymus and HSPCs from the same donor set. NOG-IL6 (n=6), NOG-EXL (n=7), and NBSGW (n=6) were assessed by flow cytometry for human CD45+CD3+ cells at 18–19 weeks post-humanization. One-way ANOVA analysis with Tukey’s multiple comparisons test was performed using GraphPad Prism software. ns=not significant, *=p<0.05, **=p<0.01.
