TABLE 2.
Overall results of the analysis of both test CTX-M-MULTI and CARBA 5 from all participant centers in direct biological samples
| Type of sample | Prevalence % |
Sensitivity % |
Specificity % |
Positive predictive value % |
Negative predictive value % |
Accuracy % |
|---|---|---|---|---|---|---|
| Urine - CTX-M | 5.9–28.5 | 84.0–100a | 98.7–100 | 92.9–100 | 97.1–100 | 96.6–100 |
|
Blood culture -
CTX-M |
7.2–28.5 | 90.9–100 | 99.6–100 | 98.2–100 | 99.1–100 | 99.0–100 |
| Rectal swab - CTX-M (without enrichment) | 6.4–28.5 | 3.4–100 | 99.7–100 | 50.5–100 | 88.0–100 | 89.4–100 |
| Rectal swab - CTX-M (enrichment) | 6.4–28.5 | 75.8–100 | 98.4–100 | 91.8–100 | 97.0–100 | 96.3–100 |
| Urine - CARBA 5 | 0–19.6 | 42.8–100 | 99.4–100 | 61.0–100 | 97.4–100 | 97.8–100 |
|
Blood culture -
CARBA 5 |
0.1–19.6 | 75.0–100 | 100 | 100 | 97.7–100 | 98.1–100 |
| Rectal swab - CARBA 5 (without enrichment) | 0.1–19.6 | 26.1–100 | 99.2–100 | 85.2–100 | 94.6–100 | 95.4–100 |
|
Rectal swab - CARBA 5 (enrichment) |
0.1–19.6 | 66.6–100 | 100 | 100 | 99.2–100 | 99.2–100 |
a
Minimal value and maximal value observed in different hospitals.