Fig. 6. (a) Weight growth curves of mice after irradiation (0–9 days, L BNCT: ¹⁰B-NapE4 + neutron irradiation for 7 minutes = radioactive dose of 1.0 Gy; M BNCT: ¹⁰B-NapE4 + neutron irradiation for 10 minutes = radioactive dose of 1.5 Gy; H BNCT: ¹⁰B-NapE4 + neutron irradiation for 14 minutes = radioactive dose of 2.0 Gy). (b) Tumor growth curves (n = 6) after irradiation (0–9 days). Statistical analysis was conducted by using the one-way ANOVA multiple comparison test with Tukey's method for tumor volumes 9 days post treatment, *p < 0.05. (c) Comparison of the explanted tumor size after 10 days of irradiation. (d) Pathological and immunohistochemical results. Representative pathological images of apoptosis and proliferation in tumor tissues. Statistical analysis of (e) Ki67, (f) γ-H2AX, and (g) P53. P values = *p < 0.05; ns: no significance. Note: the control group was not exposed to neutron irradiation with no boron delivery agents applied.