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IC50 of stimulation medium in cholangiocyte-like cell organoids (CLCOs)
| Compound solution | 24 h (μM) (Mean ± SEM) | 72 h (μM) (Mean ± SEM) |
|---|---|---|
| Cell viability | ||
| CPZ | 101.1 ± 1.2 | 70.5 ± 1.1 |
| CPZ + BA 40× | 101.2 ± 1.1 | 50.3 ± 1.1 |
| CPZ + BA 80× | 101.7 ± 1.1 | 42.2 ± 1.1 |
| Cytotoxicity (LDH release) | ||
| CPZ | 80.6 ± 1.1 | 54.1 ± 1.1 |
| CPZ + BA 40× | 77.8 ± 1.1 | 42.3 ± 1.1 |
| CPZ + BA 80× | 77.2 ± 1.0 | 52.1 ± 1.1 |
