Table 1.
Baseline patient characteristics according to surgical prophylaxis exposure
| Overall N = 46 (100) |
Standard prophylaxis N = 24 (52) |
Targeted prophylaxis N = 22 (48) |
p-value | |
|---|---|---|---|---|
| Baseline characteristics | ||||
| Age, years | 43 [33–52] | 43 [35–50] | 43 [31–55] | 0.836 |
| Male gender, n (%) | 24 (52) | 16 (67) | 8 (36) | 0.075 |
| BMI, kg/m2 | 21 [18–24] | 21 [19–24] | 20 [18–24] | 0.812 |
| Corticosteroids, n (%) | 23 (50) | 11 (46) | 12 (55) | 0.768 |
| O2 therapy, n (%) | 38 (83) | 21 (88) | 17 (77) | 0.451 |
| Diabetes, n (%) | 11 (24) | 6 (25) | 5 (23) | 0.999 |
| LAS | 35 [34–39] | 35 [34–39] | 35 [33–39] | 0.562 |
| Oto score | 3 [1–5] | 3 [1–5] | 2 [2–6] | 0.827 |
| Underlying diseases | ||||
| Septica, n (%) | 30 (65) | 15 (63) | 15 (68) | 0.763 |
| Interstitialb, n (%) | 7 (15) | 4 (17) | 3 (14) | 0.999 |
| Obstructivec, n (%) | 8 (17) | 4 (17) | 4 (18) | 0.999 |
| Othersd, n (%) | 1 (2) | 1 (4) | 0 (0) | - |
| Previous colonization | ||||
| Recipient-related MS GN bacteria | 24 (52) | 13 (58) | 9 (45) | 0.395 |
| Recipient-related MDR GN bacteria | 22 (48) | 11 (42) | 13 (55) | 0.395 |
| Donor-related GN bacteriae | 13 (28) | 8 (33) | 5 (23) | 0.521 |
| Recipient-related viral colonization | 2 (4) | 0 (0) | 2 (9) | 0.476 |
Data are expressed as number and (percentage) or median and [interquartile range]. aSeptic: cystic fibrosis, bronchiectasis; bInterstitial: idiopathic pulmonary fibrosis, allergic extrinsic alveolitis, non-specific interstitial pneumonia, fibrosing emphysema, lymphocytic interstitial pneumonia, respiratory bronchiolitis interstitial lung; cObstructive: chronic obstructive pulmonary disease; dOthers: idiopathic pulmonary hypertension, veno-occlusive disease, connective tissue disease, α1-anti-trypsin deficiency, lymphangioleiomyomatosis, histiocytosis, sarcoidosis, graft versus host disease. Abbreviations: BMI, body mass index; n, number; O2, oxygen; LAS, lung allocation score; MS, multisensitive; GN, Gram-negative; MDR, multidrug-resistant; LT, lung transplant;