Table 2.
Intraoperative characteristics according to surgical prophylaxis exposure
| Overall N = 46 (100) |
Standard prophylaxis N = 24 (52) |
Targeted prophylaxis N = 22 (48) |
p-value | |
|---|---|---|---|---|
| Intraoperative characteristics | ||||
| Time of LT, minutes | 440 [348–490] | 448 [368–490] | 430 [339–486] | 0.286 |
| Time of graft ischemia, minutes | 608 [506–755] | 570 [439–683] | 660 [523–784] | 0.038 |
| Blood transfusion, units | 2 [1–3] | 2 [1–4] | 3 [1–3] | 0.989 |
| V-A ECMO pre-emptive | 17 (37) | 12 (50) | 5 (23) | 0.072 |
| rescue | 13 (28) | 4 (17) | 9 (41) | 0.103 |
| none | 16 (35) | 8 (34) | 8 (36) | 0.999 |
| Surgical prophylaxis | ||||
| Carbapenems, n (%) | 8 (17) | 0 (0) | 8 (36) | - |
| Ceftazidime-avibactam/ceftolozane-tazobactam ect, n (%) | 10 (22) | 0 (0) | 14 (45) | - |
| β-lactam or III cephalosporins, n (%) | 24 (52) | 24 (100) | 0 (0) | - |
| Colistin, fosfomycin, fluoroquinolones, n (%) | 4 (9) | 0 (0) | 4 (18)h | - |
Data are expressed as number and (percentage) or median and ) or median and [interquartile range]. h: these antibiotics were used in combination with other antimicrobials. Abbreviations: LT, lung transplantation; V-A ECMO, venous-arterial extracorporeal membrane oxygenation