Table 2.
Coexisting extra-intestinal symptoms of male and female patients with IBS-D
| Variables | Male (n = 299) (95% CI) |
Female (n = 191) (95% CI) |
P value |
|---|---|---|---|
| GERD (%) | 153 (48.8) (45.5–56.9) | 96 (50.3) (43.1–57.4) | 0.844 |
| Heartburn (%) | 90 (30.1) (24.9–35.3) | 61 (31.9) (25.3–38.6) | 0.668 |
| Acid reflux (%) | 107 (35.8) (30.3–41.3) | 75 (39.3) (32.3–46.3) | 0.437 |
| Food regurgitation (%) | 48 (16.1) (11.9–20.2) | 18 (9.4) (5.2–13.6) | 0.036* |
| Retrosternal chest pain (%) | 27 (9.0) (5.8–12.3) | 10 (5.2) (2.0-8.4) | 0.121 |
| Functional dyspepsia (%) | 174 (58.2) (52.6–63.8) | 113 (59.2) (33.2–44.5) | 0.832 |
| Epigastric pain syndrome (%) | 103 (34.4) (29.0-39.9) | 72 (37.7) (30.8–44.6) | 0.464 |
| Epigastric pain (%) | 89 (29.8) (24.6–35) | 66 (34.6) (27.7–41.4) | 0.266 |
| Epigastric burning (%) | 38 (12.7) (8.9–16.5) | 23 (12.0) (7.4–16.7) | 0.827 |
| Postprandial distress syndrome (%) | 132 (44.1) (38.5–49.8) | 87 (45.5) (38.4–52.7) | 0.761 |
| Postprandial fullness (%) | 117 (39.1) (33.6–44.7) | 77 (40.3) (33.3–47.3) | 0.794 |
| Early satiation (%) | 44 (14.7) (10.7–18.8) | 34 (17.8) (12.3–23.3) | 0.363 |
| Headache (%) | 132 (44.1) (38.5–49.8) | 100 (52.4) (45.2–59.5) | 0.076 |
| Frequent micturition (%) | 111 (37.1) (31.6–42.6) | 52 (27.2) (20.9–33.6) | 0.023* |
| Dyspareunia (%) | 101 (33.8) (28.4–39.2) | 71 (37.2) (30.3–44.1) | 0.443 |
IBS-D, irritable bowel syndrome predominant with diarrhea; GERD, gastroesophageal reflux disease; CI, confidence interval
Data presented as number (%) (95% CI). Chi-square test. *P < 0.05