Table 2.
TLR2 gene (−196 to −174) del polymorphism and TLR1 743 A > G genotype and allele frequencies among drug resistant TB patients (PTB, MDR and XDR).
| TLR2 (−196 to-174) del polymorphism | PTB (N = 101) | MDR (N = 104) | XDR (N = 48) | Genotype frequency Chi, p, DF |
Allele frequency Chi, p, DF |
|---|---|---|---|---|---|
| I/I | 74 (0.73) | 73 (0.70) | 16 (0.33) | 27.58, 0.0001, 4 | 21.79, 0.0001, 2 |
| I/D | 23 (0.23) | 22 (0.21) | 27 (0.57) | ||
| D/D | 4 (0.04) | 9 (0.09) | 5 (0.10) | ||
| I | 171 (0.85) | 168 (0.81) | 59 (0.61) | ||
| D | 31 (0.15) | 40 (0.19) | 37 (0.38) | ||
| TLR1 743 A > G | |||||
| A/A | 29 (0.29) | 31 (0.29) | 15 (0.31) | 0.22, 0.99, 4 | 0.018, 0.99, 2 |
| A/G | 50 (0.49) | 49 (0.48) | 22 (0.46) | ||
| G/G | 22 (0.22) | 24 (0.23) | 11 (0.23) | ||
| A | 108 (0.54) | 111 (0.53) | 52 (0.54) | ||
| G | 94 (0.46) | 97 (0.47) | 44 (0.46) |