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. 2024 Mar 14;7(2 Suppl):e320. doi: 10.1097/OI9.0000000000000320

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Copyright © 2024 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Orthopaedic Trauma Association.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 2. — A and B, Preoperative radiographs of a 73-year-old woman with a distal femur nonunion 1 year after locking plate fixation of a periprosthetic distal femur fracture. Preoperative workup revealed the patient was a smoker with low vitamin D. Vitamin D supplementation and smoking cessation therapy were initiated. C and D, Radiographs 1 year postrevision fixation with an intramedullary nail and application of bone morphogenic protein-2 (BMP-2, Infuse, Medtronic, Memphis, TN) demonstrating solid union. This represents an off-label indication for the use of BMP-2.