Table I.

Demographic and clinical characteristics of the CDC Thalassemia Treatment Center Consortium cohort.

	Total		Age 18–39		Age ≥40		Chi-square P values 18–39 vs ≥40
	No.	%	No.	%	No.	%
n *	501	100	201	100	75	100
Gender							0·6606
Female	266	53·1	112	55·7	44	58·7
Male	235	46·9	89	44·3	31	41·3
Race							<0·0001
Other	36	7·2	8	4	2	2·7
Asian	256	51·1	105	52·2	9	12
White	209	41·7	88	43·8	64	85·3
Ethnicity							0·1681
Hispanic or Latino	20	4	5	2·5	0	0
Not Hispanic or Latino	479	95·6	196	97·5	75	100
Place of birth							0·1351
Non-US	145	28·9	67	33·3	18	24
US	352	70·3	134	66·7	57	76
Diagnosis							<0·0001
Beta thalassaemia intermedia	48	9·6	15	7·5	20	26·7
Beta thalassaemia major	330	65·9	142	70·6	54	72
HbE-beta thalassaemia	44	8·8	20	10	0	0
HbH	31	6·2	6	3	0	0
HbH-Constant Spring	34	6·8	14	7	1	1·3
Other	14	2·8	4	2	0	0
Age at diagnosis							0·3888
≤6 months	221	44·1	77	38·3	22	29·3
7–12 months	126	25·1	54	26·9	18	24
>1–5 years	95	19	41	20·4	23	30·7
>5 years	27	5·4	15	7·5	7	9·3
Ever had a splenectomy?							<0·0001
No	289	58	90	45	6	8
Yes	212	42	111	55	69	92
All	501	100	201	100	75	100

CDC, Centers for Disease Control and Prevention.

^*Total may not add up to 100% because of missing or unknown values.