Table 1.
Demographic and clinical characteristics of patients with and without hypoparathyroidism.
| Patients with hypoparathyroidism (Group H, n=337) |
Patients without hypoparathyroidism (Group NH, n=669) |
|
|---|---|---|
| Gender | ||
| Female | 284 (84.3) | 568 (84.9) |
| Male | 53 (15.7) | 101 (15.1) |
| Age (yr) | 45 (36-56) | 47 (37-55) |
| Time of follow-up (yr) | 8.9 (6.0-13.0) | 8.0 (5.3-12.0) |
| Total thyroidectomy | ||
| One-stage | 302 (89.6) | 567 (84.8) |
| Two-stage | 35 (10.4) | 102 (15.2) |
| Thyroid histopathology | ||
| Benign thyroid disease |
112 (33.2) | 120 (17.9) |
| Thyroid cancer | 225 (66.8) | 549 (82.1) |
| Benign thyroid disease | ||
| Graves’ disease | 18 (16.1) | 23 (19.2) |
| Follicular nodular disease |
73 (65.2) | 75 (62.5) |
| Chronic lymphocytic thyroiditis |
14 (12.5) | 13 (10.8) |
| Other | 7 (6.3) | 9 (7.5) |
| Thyroid cancer | ||
| Papillary | 194 (86.2) | 476 (86.7) |
| Follicular | 18 (8.0) | 45 (8.2) |
| Oncocytic | 3 (1.3) | 9 (1.6) |
| Other | 10 (4.4) | 19 (3.5) |
| Chronic kidney disease | 7 (2.1) | 15 (2.2) |
| Nephrolithiasis | 4 (1.2) | 13 (1.9) |
| Arterial hypertension | 55 (16.3) | 121 (18.1) |
| Dyslipidemia | 65 (19.3) | 139 (20.8) |
| Diabetes | 15 (4.5) | 41 (6.1) |
| Cardiovascular disease | 10 (3.0) | 25 (3.7) |
| Coronary heart disease |
3 (0.9) | 8 (1.2) |
| Cerebrovascular disease |
1 (0.3) | 7 (1.0) |
| Other | 7 (2.1) | 12 (1.8) |
| Central nervous system disease | 6 (1.8) | 12 (1.8) |
| Mental health disorders | 44 (13.1) | 93 (13.9) |
| Eye disorders | 11 (3.3) | 14 (2.1) |
| Bone mineral density alterations | 8 (2.4) | 22 (3.3) |
| Fracture | 3 (0.9) | 6 (0.9) |
| Cancer | 18 (5.3) | 33 (4.9) |
Data are the median (IQR) for quantitative variables. For categorical variables, the absolute value is represented and, in parentheses, the prevalence in patients with hypoparathyroidism and the proportion in patients without hypoparathyroidism.
The percentages of the different types of benign thyroid disease and thyroid cancer are calculated for the total of these histological types in patients with (112 benign and 125 malignant) and patients without hypoparathyroidism (120 benign and 549 malignant).