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. 2024 Feb 28;15:1348971. doi: 10.3389/fendo.2024.1348971

Table 2.

Obtained values of cumulative incidence and incidence rates of incident comorbidities in patients with hypoparathyroidism and proportion of patients without hyperparathyroidism who develop incident comorbidities.

Patients with hypoparathyroidism (group H) Patients without hypoparathyroidism (group NH) Odds ratio
Cumulative incidence (%) Incidence rate
(per 100 patient-year)
Proportion (%) Value P
Chronic kidney disease 7.27
(4.47-10.07)
0.73
(0.44-1.02)
2.60
(1.38-3.82)
2.94
(1.56-5.55)
0.001
Nephrolithiasis 5.41
(2.98-7.83)
0.54
(0.29-0.79
1.83
(0.80-2.85)
3.07
(1.46-6.45)
0.003
Hypertension 15.25
(11.05-19.44)
1.58
(1.11-2.05)
19.53
(16.21-22.84)
0.74
(0.50-1.09)
0.130
Dyslipidemia 20.22
(15.45-24.29)
2.14
(1.57-2.70)
22.08
(18.54-25.61)
0.90
(0.62-1.28)
0.545
Diabetes 7.14
(/4.33-9.96)
0.72
(0.43-1.02)
6.69
(4.73-8.64)
1.07
(0.63-1.82)
0.793
Cardiovascular disease 8.26
(5.27-11.24)
0.84
(0.52-1.16)
4.35
(2.27-5.92)
1.98
(1.15-3.42)
0.014
Coronary heart disease 2.10
(0.56-3.63)
0.21
(0.05-0.36)
1.21
(0.38-2.04)
1.75
(0.63-4.86)
0.285
Cerebrovascular disease 2.98
(1.16-4.79)
0.30
(0.11-0.48)
1.36
(0.48-2.24)
2.23
(0.90-5.53)
0.085
Other cardiovascular disease 4.24
(2.07-6.42)
0.42
(0.20-0.65)
2.89
(1.61-4.17)
1.49
(0.74-3.01)
0.268
Central nervous system disease 0.30
(0-0.89)
0.03
(0-0.09)
0.46
(0-0.97)
0.66
(0.07-6.38)
0.720
Mental health disorders 15.36
(11.23-19.49)
1.61
(1.14-2.08)
12.85
(10.11-15.58)
1.23
(0.82-1.84)
0.309
Eye disorders 4.60
(2.33-6.88)
0.45
(0.22-0.68)
3.66
(2.23-5.10)
1.27
(0.66-2.45)
0.480
BMD alterations 6.38
(3.74-9.02)
0.64
(0.37-0.92)
5.72
(3.93-7.51)
1.12
(0.65-1.95)
0.678
Fracture 0.30
(0-0.89)
0.03
(0-0.09)
3.02
(1.71-4.32)
0.10
(0.01-0.72)
0.023
Cancer 5.64
(3.11-8.17)
0.57
(0.31-0.83)
7.39
(5.36-9.42)
0.75
(0.43-1.31)
0.313

Data are the value of the parameter indicated with the 95% confidence interval in parentheses.

BMD, bone mineral density.