Table 3.
Pharmacological treatments used by patients before thyroidectomy and at the last follow-up visit.
| Before thyroidectomy | Last visit | Comparison last visit vs. before surgery | ||||||
|---|---|---|---|---|---|---|---|---|
| Group H | Group NH | Group H | Group NH | Group H | Group NH | |||
| P | P | P | P | |||||
| Calcium | 9 (2.7) | 17 (2.5) | 0.526 | 296 (87.8) | 57 (8.5) | <0.001 | <0.001 | <0.001 |
| Calcitriol | 332 (98.5) | 0 (0) | <0.001 | |||||
| Levothyroxine | 32 (9.5) | 44 (6.6) | 0.066 | 337 (100) | 669 (100) | |||
| Vitamin D | 21 (6.2) | 26 (3.9) | 0.068 | 138 (40.9) | 238 (35.6) | 0.098 | <0.001 | <0.001 |
| Hypolipidemic drugs | 48 (14.2) | 101 (15.1) | 0.394 | 91 (27.0) | 200 (29.9) | 0.337 | <0.001 | <0.001 |
| Oral antidiabetics | 13 (3.9) | 35 (5.2) | 0.211 | 32 (9.5) | 67 (10.0) | 0.824 | <0.001 | <0.001 |
| Injectable antidiabetics | 2 (0.6) | 4 (0.6) | 0.677 | 10 (3.0) | 18 (2.7) | 0.840 | 0.008 | 0.001 |
| Insulin | 3 (0.9) | 9 (1.3) | 0.387 | 5 (1.5) | 15 (2.2) | 0.482 | 0.500 | 0.109 |
| Thiazide diuretics | 16 (4.7) | 32 (4.8) | 0.562 | 65 (19.3) | 93 (13.9) | 0.028 | <0.001 | <0.001 |
| Non thiazide diuretics | 11 (3.3) | 12 (1.8) | 0.108 | 19 (5.6) | 37 (5.5) | 1.000 | 0.057 | <0.001 |
| Beta-blockers | 11 (3.3) | 27 (4.0) | 0.339 | 29 (8.6) | 51 (7.6) | 0.622 | <0.001 | <0.001 |
| Calcium antagonists | 20 (5.9) | 28 (4.2) | 0.142 | 30 (8.9) | 64 (9.6) | 0.819 | 0.064 | <0.001 |
| ACE inhibitors | 36 (10.7) | 91 (13.6) | 0.111 | 70 (20.8) | 181 (27.1) | 0.031 | <0.001 | <0.001 |
| Antiarrhythmics | 1 (0.3) | 4 (0.6) | 0.457 | 4 (1.2) | 9 (1.3) | 1.000 | 0.375 | 0.227 |
| Oral anticoagulants | 1 (0.3) | 6 (0.9) | 0.259 | 8 (2.4) | 14 (2.1) | 0.821 | 0.016 | 0.039 |
| Anxiolytics | 35 (10.4) | 63 (9.4) | 0.350 | 62 (18.4) | 130 (19.4) | 0.734 | <0.001 | <0.001 |
| Antidepressants | 18 (5.3) | 43 (6.4) | 0.298 | 38 (11.3) | 87 (13.0) | 0.479 | 0.001 | <0.001 |
| Antipsychotics | 4 (1.2) | 9 (1.3) | 0.547 | 5 (1.5) | 14 (2.1) | 0.627 | 1.000 | 0.125 |
Data are the number of patients (percentage) in each pharmacological group.
ACE, angiotensin-converting enzyme.