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. 2024 Feb 28;15:1348971. doi: 10.3389/fendo.2024.1348971

Table 3.

Pharmacological treatments used by patients before thyroidectomy and at the last follow-up visit.

Before thyroidectomy Last visit Comparison last visit vs. before surgery
Group H Group NH Group H Group NH Group H Group NH
P P P P
Calcium 9 (2.7) 17 (2.5) 0.526 296 (87.8) 57 (8.5) <0.001 <0.001 <0.001
Calcitriol 332 (98.5) 0 (0) <0.001
Levothyroxine 32 (9.5) 44 (6.6) 0.066 337 (100) 669 (100)
Vitamin D 21 (6.2) 26 (3.9) 0.068 138 (40.9) 238 (35.6) 0.098 <0.001 <0.001
Hypolipidemic drugs 48 (14.2) 101 (15.1) 0.394 91 (27.0) 200 (29.9) 0.337 <0.001 <0.001
Oral antidiabetics 13 (3.9) 35 (5.2) 0.211 32 (9.5) 67 (10.0) 0.824 <0.001 <0.001
Injectable antidiabetics 2 (0.6) 4 (0.6) 0.677 10 (3.0) 18 (2.7) 0.840 0.008 0.001
Insulin 3 (0.9) 9 (1.3) 0.387 5 (1.5) 15 (2.2) 0.482 0.500 0.109
Thiazide diuretics 16 (4.7) 32 (4.8) 0.562 65 (19.3) 93 (13.9) 0.028 <0.001 <0.001
Non thiazide diuretics 11 (3.3) 12 (1.8) 0.108 19 (5.6) 37 (5.5) 1.000 0.057 <0.001
Beta-blockers 11 (3.3) 27 (4.0) 0.339 29 (8.6) 51 (7.6) 0.622 <0.001 <0.001
Calcium antagonists 20 (5.9) 28 (4.2) 0.142 30 (8.9) 64 (9.6) 0.819 0.064 <0.001
ACE inhibitors 36 (10.7) 91 (13.6) 0.111 70 (20.8) 181 (27.1) 0.031 <0.001 <0.001
Antiarrhythmics 1 (0.3) 4 (0.6) 0.457 4 (1.2) 9 (1.3) 1.000 0.375 0.227
Oral anticoagulants 1 (0.3) 6 (0.9) 0.259 8 (2.4) 14 (2.1) 0.821 0.016 0.039
Anxiolytics 35 (10.4) 63 (9.4) 0.350 62 (18.4) 130 (19.4) 0.734 <0.001 <0.001
Antidepressants 18 (5.3) 43 (6.4) 0.298 38 (11.3) 87 (13.0) 0.479 0.001 <0.001
Antipsychotics 4 (1.2) 9 (1.3) 0.547 5 (1.5) 14 (2.1) 0.627 1.000 0.125

Data are the number of patients (percentage) in each pharmacological group.

ACE, angiotensin-converting enzyme.