Table 3.
The following values, measured on the second post-operative day after the first (BDL or sham) or second surgery (balloon dilatation of the carotid artery), are given for both study groups (BDL or sham): absolute bodyweight, daily analgesic requirement as assessed by the observer and score points for bodyweight, general condition, spontaneous behaviour and overall score. The three animals that died due to intraoperative complications during the 2nd surgery were excluded
| 1st surgery | 2nd surgery | |||||||
|---|---|---|---|---|---|---|---|---|
| Sham | BDL | Sham | BDL | |||||
| dead | survived | df | P-value | Cohen’s d | ||||
| (n = 40) | (n = 7) | (n = 39) | (n = 40) | (n = 39) | ||||
| BW absolute (g) | 460 (± 28) | 429 (± 18) | 455 (± 36) | 44 | 0.07 | 33.9 | 512 (± 32) | 514 (± 50) |
| BW (score points) | 5.6 (± 2.0) | 9.2 (± 1.9) | 5.8 (± 1.8) | 44 | < 0.001 | 1.84 | 6.0 (± 2.3) | 6.8 (± 2.7) |
| GC (score points) | 0.5 (± 1.5) | 2.7 (± 2.1) | 0.5 (± 1.5) | 44 | 0.031 | 1.56 | 0.4 (± 1.1) | 1.2 (± 3.5) |
| Sp-B (score points) | 0 (± 0) | 1.7 (± 2.4) | 0 (± 0) | 44 | < 0.001 | 0.89 | 0.2 (± 0.9) | 0.7 (± 2.4) |
| PS (score points) | 0 (± 0) | 0 (± 0) | 0 (± 0) | – | – | – | 0 (± 0) | 0 (± 0) |
| Overall score (points) | 6.1 ± (2.5) | 13.7 (± 4.7) | 6.3 (± 2.7) | 44 | < 0.001 | 3.08 | 6.4 (± 2.7) | 8.5 (± 6.6) |
| DARAO (n) | 0.1 (± 0.2) | 1.2 (± 0.8) | 0.1 (± 0.2) | 43 | 0.015 | 0.33 | 0 (± 0) | 0.1 (± 0.3) |
Values are presented as means (± SD). P-values of the comparison (t-test) between values of animals that died prematurely or that were euthanased (grouped together under the heading ‘dead’) and those that survived, are given. BW: bodyweight; DARAO: daily analgesic requirement as assessed by the observer; GC: general condition; Sp-B: spontaneous behaviour; PS: procedure specific, df: degrees of freedom.