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. 2024 Mar 12;14(3):e072300. doi: 10.1136/bmjopen-2023-072300

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© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Estimated response rates at 12 months (CARRAC), Swiss Clinical Quality Management registry, 2017–2020. BARI, baricitinib; LDA, low disease activity (ie, CDAI score ≤ 10), in light grey; CARRAC, confounder-adjusted response rate with attrition correction; OMA, other modes of action bDMARDs; REM, remission (ie, CDAI score ≤ 2.8), in dark grey; TNFi, tumour necrosis factor inhibitors. 95% CI, are represented. This method does not allow computing p values. Nb: two estimates were obtained in the BARI group and averaged to display only one representative value on the plot. Actual row output was 68% (95%CI 55% to 80%) (BARI vs TNFi model) or 62% (95% CI, 54 to 70) (BARI vs OMA model) for LDA and 23% (95% CI, 14 to 31) (BARI vs TNFi model) or 17% (95% CI, 10 to 24) (BARI vs OMA model) for REM.