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. 2024 Mar 13;14(3):e081926. doi: 10.1136/bmjopen-2023-081926

Figure 3.

Figure 3

Kaplan-Meier curves for the cumulative incidence of (A) mortality, (B) liver disease, (C) any joint replacement and (D) any brain outcome, in male HFE p.C282Y homozygotes compared with those with no mutations. Cumulative incidence (estimated % diagnosed by age 80 years; 95% CIs). Joint replacement surgery includes a diagnosis of hip, knee, ankle or shoulder replacement. Any brain outcome included a diagnosis of delirium, dementia or Parkinson’s disease.