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. 2024 Feb 23;15:1368620. doi: 10.3389/fphar.2024.1368620

FIGURE 3.

FIGURE 3

FST results show that CORT elevated FST immobility time and was recovered in females, irrespective of the cohort and partially recovered in males exposed to 2.6 cycles with Reelin. (A) FST results of female rats exposed to 1.3 cycles demonstrating significantly increased immobility with CORT that was reversed by Reelin. (B) FST results showing that behavioral deficits remained after factoring in individual body mass data. (C) FST results showing that CORT induced behavioral despair in both males and females that was recovered with Reelin treatment. (D) FST results of rats exposed to 2.6 cycles after factoring in individual body mass, showing that males and females exposed to CORT still show evidence of behavioral despair that was partially recovered with Reelin treatment and that females treated with CORT/vehicle were more immobile than their male counterparts after factoring in individual body mass.