Fig. 3. Selected metabolic maps, plots of overall metabolic concentrations over time, and accompanying ¹H anatomic image, arising from experiments on a mouse having three PDAC tumors, subjected to different deuterated pyruvate and glucose injection protocols over the course of a 10-hour experiment.

The colors (red, orange, purple, and blue) reflect signals arising from the corresponding regions marked on the ¹H anatomical image; dotted lines indicate the moments of the various injections. The concentration dependencies also indicate the timing and the amounts of glucose injected over the course of this experiment. Notice the different patterns evidenced by the deuterated lactate produced by the pyruvate and glucose injections, the different color maps accompanying each set of injections, as well as the growing amounts of lactate produced from increasing amounts of glucose injection: Only the tumor circled in purple exhibits some sort of “saturation” between the second and third injections.