FIGURE 2.

Kidney function during ex vivo perfusion. A, Urine output at the indicated time during NMP with WE or packed RBCs. B, Percentage of creatinine remaining in the perfusate over time in both groups as indicated. Lactate levels at each time point (C) and slope (D) measured in the venous outflow of kidneys perfused with WE or RBCs. Black lines indicate simple linear regression and 95% CI. Bars indicate mean ± SEM, and asterisks indicate the significance of the difference between perfusion methods by Mann-Whitney tests. ***P < 0.001. n = 5–11 per group. CI, confidence interval; RBC, packed red blood cell; WE, William’s E medium.