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. Author manuscript; available in PMC: 2024 Dec 1.
Published in final edited form as: J Arthroplasty. 2023 Jun 7;38(12):2710–2715.e2. doi: 10.1016/j.arth.2023.05.092

Table 1:

McPherson Host Staging System for Periprosthetic Joint Infection

Category Grade Description

Infection type I Acute early postoperative infection
II Acute hematogenous infection
III Late chronic infection
Systemic host grade A Uncompromised
B Compromised (1–2 compromising factors)
Severely compromised (>2 compromising factors) or one of the following:
Absolute neutrophil count < 1000
C CD4 T cell count < 100
Intravenous drug abuse
Chronic active infection, other site
Dysplasia or neoplasm of the immune system
Local extremity grade 1 Uncompromised
2 Compromised (1–2 compromising factors)
3 Significant compromise (>2 compromising factors)

Table adapted from McPherson et al. [11]