Table 3.

Univariate Cox Regression Risk Analysis

Variable	Reoperation for Infection		Any Reoperation		Re-revision for Infection		Any Re-revision		Death
	HR (95% CI)	p-value	HR (95% CI)	p-value	HR (95% CI)	p-value	HR (95% CI)	p-value	HR (95% CI)	p-value
Men (vs. women)	1.5 (0.5, 4.6)	0.45	1.3 (0.49, 3.4)	0.6	1.9 (0.48, 7.3)	0.37	1.2 (0.4, 3.4)	0.77	1.2 (0.5, 2.6)	0.68
BMI ≥ 30 kg/m2 (vs. BMI < 30 kg/m2)	1.2 (0.4, 3.7)	0.73	1.4 (0.51, 3.7)	0.52	2.2 (0.56, 8.9)	0.26	1.9 (0.62, 5.5)	0.27	0.78 (0.36, 1.7)	0.53
Age at IDCR < 70 years (vs. age ≥ 70)	1.9 (0.64, 5.8)	0.25	1.6 (0.6, 4.2)	0.35	4.4 (0.92, 21)	0.06	2.1 (0.7, 6.2)	0.18	0.48 (0.22, 1)	0.06
Host B (vs. A)	1.8 (0.32, 10)	0.51	1.8 (0.47, 7.1)	0.38	3.1 (0.31, 32)	0.33	2.6 (0.55, 12)	0.23	5.7 (1.1, 29)	0.035
Host C (vs. A)	5.3 (1.1, 26.1)	0.04	4.2 (1.14, 15.7)	0.03	7.5 (0.74, 75)	0.09	5.7 (1.3, 26)	0.025	13 (2.3, 76)	0.004
Host C (vs. B)	2.9 (0.96, 8.9)	0.06	2.3 (0.84, 6.4)	0.11	2.4 (0.66, 8.7)	0.19	2.3 (0.72, 7)	0.16	2.4 (1.1, 5.3)	0.038
Acute early infection (vs. acute hematogenous)	2 (0.67, 5.7)	0.22	1.6 (0.59, 4.3)	0.36	2.1 (0.57, 7.4)	0.27	1.8 (0.61, 5.5)	0.28	0.92 (0.42, 2)	0.83
Multiple prior aseptic revisions (vs. single)	1.7 (0.56, 5.3)	0.35	1.9 (0.68, 5.1)	0.22	2.2 (0.54, 8.8)	0.28	2.6 (0.82, 8.3)	0.10	0.95 (0.45, 2)	0.9
Single IDCR (vs. double)	0.71 (0.23, 2.2)	0.56	0.85 (0.28, 2.6)	0.77	0.75 (0.19, 3.1)	0.69	1.1 (0.28, 4.2)	0.92	1.7 (0.63, 4.5)	0.29
Rifampin treated (vs. no rifampin)	0.77 (0.2, 2.9)	0.7	0.95 (0.27, 3.4)	0.94	2.24 (0.4, 13)	0.36	1.9 (0.43, 7.9)	0.41	----	----
Staphylococcus organism (vs. not)	1.4 (0.45, 4.2)	0.58	0.99 (0.38, 2.5)	0.98	1.2 (0.33, 4.5)	0.77	0.92 (0.33, 2.6)	0.88	1.7 (0.63, 4.5)	0.29

^*HR = Hazard Ratio; CI = Confidence Interval; BMI = Body Mass Index; IDCR = Irrigation and Debridement with Component Retention