Table 3.
Differences in ESS metrics between plaque erosion and control groups.
| Characteristic | Erosion (N = 24) | Control (N = 22) | p-value |
|---|---|---|---|
| Mean coronary flow (ml/sec) | 0.7 ± 0.3 | 0.6 ± 0.3 | 0.19 |
| 90° Arc Min ESS/plaque (Pa) | 0.8 ± 0.5 | 0.6 ± 0.4 | 0.40 |
| 90° Arc Max ESS/plaque (Pa) | 8.3 ± 4.8 | 5.0 ± 1.9 | 0.02 |
| 90° Arc Average ESS/plaque (Pa) | 3.9 ± 2 | 3.0 ± 1.29 | 0.18 |
| Max ESSG any direction (Pa/mm) | 9.2 ± 7.5 | 4.3 ± 3.1 | 0.005 |
| Max ESSG plaque upslope (Pa/mm) | 5.0 ± 6.1 | 2.1 ± 2.3 | 0.009 |
| Max ESSG plaque downslope (Pa/mm) | 7.0 ± 7.0 | 3.5 ± 3.1 | 0.16 |
| Max ESSG circumferential (Pa/mm) | 4.0 ± .3.3 | 1.9 ± 1.4 | 0.003 |
| Thrombus location vs. minimal lumen area location in erosion group | |||
| Thrombus location in culprit plaque | Δ Lumen area UPSLOPE (mm2/frame) | Δ Lumen area DOWNSLOPE (mm2/frame) | p-value |
| Proximal to the MLA (n = 10) | 2.2 ± 1.2 | 1.07 ± 0.8 | 0.005 |
| Distal to the MLA (n = 10) | 2.1 ± 0.4 | 3.93 ± 1.8 | 0.005 |
| Across the MLA (n = 4) | 2.5 ± 0.9 | 1.8 ± 0.7 | 0.14 |
| Max Absolute Slope Value | 2.2 ± 1.2 | 3.93 ± 1.8 | 0.007 |
Values are presented as mean ± SD for continuous variables. ESS = endothelial shear stress; ESSG = endothelial shear stress gradient; MLA = minimal lumen area.