Figure 2.

Body weight and body composition in NCD fed mice. (A) Development of body weight over 24 weeks. (B) Body fat and (C) lean mass measured by ¹H nuclear magnetic resonance (NMR) at 4 and 24–25 weeks of age. (D) Weight of epigonadal white adipose tissue (eWAT), subcutaneous white (sWAT), perirenal white (pWAT) and brown adipose tissue (BAT). (E) Blood glucose level and (F) plasma insulin level during ipGTT in 12-week-old animals. (G) Glucose infusion rate (GIR), (H) peripheral glucose uptake and, (I) free fatty acids (FFA) during hyperinsulinemic-euglycemic clamp in 26-week-old mice. Data represents mean ± SEM (n = 6–10).