Figure 7.

Wnt/β-catenin pathway in tissues of HFD mice. (A) Representative Western Blots for non-phospho (active), total β-catenin and β-actin protein abundance in liver of WT and hKST-TG mice (n = 3). (B-D) Densitometry analysis of total β-catenin (B), non-phospho (active) β-catenin (C) and, active/total β-catenin ratio (D) normalized to β-actin. (E–G) Gene expression of Wnt-signaling targets in liver (E), muscle (F) and, eWAT (G). Data represents mean ± SEM (n = 3–10). ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.