Table 2.
Multivariate analysis of factors associated with poor body image, sexual inactivity, poor sexual functioning, and poor sexual enjoyment
| Exposable variable | Body image |
Sexual functioning |
Sexually inactive |
Sexual enjoyment |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | |
| Age, <40 years versus >65 years | 1.08 | 0.86-1.36 | 0.460 | 0.17 | 0.12-0.23 | <0.0001 | 0.18 | 0.13-0.24 | <0.0001 | 0.49 | 0.34-0.71 | 0.001 |
| Age, 40-49 years versus >65 years | 1.12 | 0.95-1.31 | 0.152 | 0.22 | 0.18-0.27 | <0.0001 | 0.22 | 0.18-0.27 | <0.0001 | 0.81 | 0.60-1.08 | 0.160 |
| Age, 50-64 years versus >65 years | 1.02 | 0.90-1.16 | 0.658 | 0.49 | 0.43-0.57 | <0.0001 | 0.49 | 0.43-0.57 | <0.0001 | 0.85 | 0.66-1.11 | 0.260 |
| Marital status, partnered versus not partnered | 0.95 | 0.83-1.09 | 0.519 | 2.22 | 1.89-2.60 | <0.0001 | 2.29 | 1.95-2.68 | <0.0001 | 0.74 | 0.51-1.07 | 0.112 |
| Education, high versus primary school | 1.13 | 1.01-1.26 | 0.027 | 1.02 | 0.89-1.16 | 0.715 | 1.02 | 0.90-1.16 | 0.673 | 0.95 | 0.80-1.13 | 0.578 |
| Education, college versus primary school | 0.73 | 0.62-0.86 | 0.001 | 1.10 | 0.91-1.33 | 0.300 | 1.14 | 0.95-1.38 | 0.149 | 1.58 | 1.09-2.30 | 0.015 |
| Monthly income, ≥1500-<3000 euros versus <1500 euros | 1.10 | 0.98-1.23 | 0.076 | 0.86 | 0.75-0.98 | 0.031 | 0.84 | 0.73-0.96 | 0.011 | 0.85 | 0.72-1.01 | 0.079 |
| Monthly income, ≥3000 euros versus <1500 euros | 1.04 | 0.88-1.22 | 0.626 | 1.20 | 0.99-1.45 | 0.056 | 1.22 | 1.01-1.48 | 0.031 | 1.09 | 0.76-1.54 | 0.627 |
| Comorbidity score, ≥1 versus 0 | 1.00 | 0.88-1.14 | 0.914 | 1.04 | 0.90-1.21 | 0.525 | 1.03 | 0.89-1.19 | 0.649 | 0.95 | 0.76-1.18 | 0.668 |
| Smoke behavior, current versus never | 1.19 | 1.05-1.34 | 0.003 | 0.97 | 0.84-1.13 | 0.779 | 0.96 | 0.83-1.10 | 0.601 | 0.87 | 0.72-1.06 | 0.180 |
| Smoke behavior, former versus never | 1.33 | 1.16-1.53 | <0.0001 | 1.08 | 0.92-1.27 | 0.322 | 1.09 | 0.93-1.29 | 0.256 | 0.81 | 0.65-1.02 | 0.075 |
| Daily alcohol consumption, yes versus no | 1.00 | 0.87-1.15 | 0.923 | 0.99 | 0.84-1.17 | 0.940 | 0.99 | 0.84-1.17 | 0.941 | 0.92 | 0.73-1.16 | 0.506 |
| BMI, ≥25 kg/m2 versus <25 kg/m2 | 1.24 | 1.12-1.37 | <0.0001 | 1.13 | 1.01-1.28 | 0.032 | 1.12 | 0.99-1.26 | 0.054 | 0.96 | 0.81-1.13 | 0.627 |
| Level of physical activity, sufficiently versus insufficiently active | 1.04 | 0.94-1.14 | 0.405 | 0.99 | 0.88-1.11 | 0.869 | 1.01 | 0.90-1.14 | 0.740 | 1.04 | 0.89-1.22 | 0.585 |
| Chemotherapy, yes versus no | 1.88 | 1.68-2.10 | <0.0001 | 1.19 | 1.03-1.36 | 0.013 | 1.16 | 1.01-1.33 | 0.029 | 0.99 | 0.81-1.20 | 0.928 |
| Endocrine therapy, yes versus no | 1.15 | 1.01-1.31 | 0.026 | 1.19 | 1.02-1.39 | 0.023 | 1.17 | 1.01-1.37 | 0.032 | 1.23 | 1.00-1.53 | 0.046 |
| Use of ovarian function suppression, yes versus no | 0.98 | 0.70-1.37 | 0.912 | 1.33 | 0.91-1.93 | 0.128 | 1.37 | 0.95-1.98 | 0.091 | 1.03 | 0.63-1.67 | 0.885 |
| Anti-HER2 therapy, yes versus no | 0.99 | 0.84-1.15 | 0.913 | 1.10 | 0.91-1.34 | 0.299 | 1.14 | 0.94-1.38 | 0.181 | 1.28 | 1.02-1.62 | 0.031 |
| Radiotherapy, yes versus no | 0.79 | 0.64-0.97 | 0.029 | 0.92 | 0.73-1.17 | 0.533 | 0.93 | 0.74-1.17 | 0.546 | 1.01 | 0.72-1.42 | 0.944 |
| Axillary surgery, dissection versus sentinel/no | 1.08 | 0.96-1.21 | 0.171 | 1.00 | 0.87-1.15 | 0.977 | 1.02 | 0.89-1.17 | 0.751 | 1.09 | 0.90-1.32 | 0.332 |
| Breast surgery, mastectomy versus conservative | 1.99 | 1.74-2.28 | <0.0001 | 1.05 | 0.89-1.24 | 0.502 | 1.04 | 0.88-1.22 | 0.629 | 1.09 | 0.88-1.35 | 0.406 |
| Anxiety (at T1), doubtful/case versus noncase | 1.80 | 1.62-1.99 | <0.0001 | 0.91 | 0.80-1.03 | 0.152 | 0.91 | 0.80-1.04 | 0.181 | 0.99 | 0.84-1.17 | 0.959 |
| Depression (at T1), doubtful/case versus noncase | 2.00 | 1.72-2.34 | <0.0001 | 1.66 | 1.40-1.97 | <0.0001 | 1.69 | 1.43-2.00 | <0.0001 | 1.94 | 1.50-2.51 | <0.0001 |
| Vaginal dryness (at T1), yes versus no | 1.16 | 1.05-1.29 | 0.002 | 0.73 | 0.64-0.82 | <0.0001 | 0.73 | 0.64-0.83 | <0.0001 | 1.82 | 1.55-2.14 | <0.0001 |
| Hot flashes (at T1), yes versus no | 1.22 | 1.10-1.35 | <0.0001 | 1.02 | 0.90-1.15 | 0.694 | 1.01 | 0.89-1.14 | 0.819 | 1.20 | 1.01-1.43 | 0.037 |
| Poor role functioning (at T1), yes versus no | 0.89 | 0.75-1.06 | 0.204 | 1.04 | 0.85-1.27 | 0.700 | 1.05 | 0.86-1.29 | 0.578 | 0.97 | 0.73-1.29 | 0.857 |
| Poor social functioning (at T1), yes versus no | 1.65 | 1.39-1.97 | <0.0001 | 1.22 | 0.98-1.50 | 0.063 | 1.17 | 0.95-1.45 | 0.117 | 1.24 | 0.92-1.66 | 0.147 |
| Severe fatigue (at T1), yes versus no | 1.48 | 1.31-1.67 | <0.0001 | 1.07 | 0.92-1.25 | 0.318 | 1.11 | 0.95-1.28 | 0.163 | 1.21 | 0.99-1.48 | 0.053 |
| Severe pain (at T1), yes versus no | 1.31 | 1.14-1.50 | <0.0001 | 1.13 | 0.96-1.34 | 0.123 | 1.13 | 0.96-1.33 | 0.138 | 1.12 | 0.90-1.40 | 0.302 |
| Severe insomnia (at T1), yes versus no | 1.16 | 1.04-1.29 | 0.005 | 1.13 | 1.00-1.29 | 0.050 | 1.13 | 1.00-1.29 | 0.048 | 1.17 | 0.98-1.40 | 0.081 |
| Consultation with a gynecologist (at T1), yes versus no | 0.99 | 0.89-1.10 | 0.919 | 0.74 | 0.65-0.84 | <0.0001 | 0.75 | 0.66-0.86 | <0.0001 | 0.81 | 0.69-0.95 | 0.011 |
| Consultation with a psychiatrist/psychologist (at T1), yes versus no | 1.11 | 0.97-1.27 | 0.099 | 1.11 | 0.94-1.31 | 0.205 | 1.10 | 0.94-1.30 | 0.214 | 0.96 | 0.78-1.17 | 0.698 |
| Sexual concern (at T0), yes versus no | 3.48 | 3.11-3.89 | <0.0001 | 9.94 | 8.84-11.1 | <0.0001 | 9.75 | 8.67-10.9 | <0.0001 | 3.96 | 3.34-4.69 | <0.0001 |
BMI, body mass index; CI, confidence interval; HER2, human epidermal growth factor receptor 2; OR, odds ratio; T0, at the moment of diagnosis; T1, year 1 after diagnosis.