Figure 4.

Breastcancer deaths among patients stratified by LVI and sTILs. The effects of LVI (presence versus absence of LVI) on breast cancer-specific death in the different sTILs categories were estimated with a Cox proportional hazard model that included an interaction term between LVI and sTILs. The total effect of LVI was estimated with a univariable Cox proportional hazard model. Patients with missing information on sTILs (n = 4) were excluded from analyses. BCSS, breast cancer-specific survival; CI, confidence interval; HR, hazard ratio; LVI, lymphovascular invasion; sTILs, stromal tumor-infiltrating lymphocytes.